Musculoskeletal

Dynamic Gadolinium-Enhanced Magnetic Resonance Imaging Allows Accurate Assessment of the Synovial Inflammatory Activity in Rheumatoid Arthritis Knee Joints: A Comparison with Synovial Histology

Publications

Dynamic Gadolinium-Enhanced Magnetic Resonance Imaging Allows Accurate Assessment of the Synovial Inflammatory Activity in Rheumatoid Arthritis Knee Joints: A Comparison with Synovial Histology

Maecenas tempor, ex at maximus efficitur, felis sem ultrices ligula, ut hendrerit purus eros ac urna. Vestibulum ut vestibulum tortor. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Cras eu lectus quam. Nunc ligula arcu, auctor sit amet tellus eleifend, facilisis laoreet odio. Donec placerat urna eleifend blandit porttitor.

Nunc magna turpis, tristique at dictum vel, sollicitudin blandit felis. Morbi aliquam elit et pellentesque vulputate. Donec elementum, ante quis ornare porttitor, tortor dolor vestibulum velit, et viverra enim massa vitae ex.

Separation of Active Early Rheumatoid Arthritis Patients and Healthy Controls by Conventional and Dynamic Contrast-Enhanced MRI

Publications

Separation of Active Early Rheumatoid Arthritis Patients and Healthy Controls by Conventional and Dynamic Contrast-Enhanced MRI

Maecenas tempor, ex at maximus efficitur, felis sem ultrices ligula, ut hendrerit purus eros ac urna. Vestibulum ut vestibulum tortor. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Cras eu lectus quam. Nunc ligula arcu, auctor sit amet tellus eleifend, facilisis laoreet odio. Donec placerat urna eleifend blandit porttitor.

Nunc magna turpis, tristique at dictum vel, sollicitudin blandit felis. Morbi aliquam elit et pellentesque vulputate. Donec elementum, ante quis ornare porttitor, tortor dolor vestibulum velit, et viverra enim massa vitae ex.

Duration of Improvement Following Rituximab Treatment in Rheumatoid Arthritis is not Predicted by Wrist MRI

Publications

Duration of Improvement Following Rituximab Treatment in Rheumatoid Arthritis is not Predicted by Wrist MRI

Maecenas tempor, ex at maximus efficitur, felis sem ultrices ligula, ut hendrerit purus eros ac urna. Vestibulum ut vestibulum tortor. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Cras eu lectus quam. Nunc ligula arcu, auctor sit amet tellus eleifend, facilisis laoreet odio. Donec placerat urna eleifend blandit porttitor.

Nunc magna turpis, tristique at dictum vel, sollicitudin blandit felis. Morbi aliquam elit et pellentesque vulputate. Donec elementum, ante quis ornare porttitor, tortor dolor vestibulum velit, et viverra enim massa vitae ex.

Chronic Recurrent Multifocal Osteomyelitis in Children: A New, MRI-Based Method of Quantifying Inflammation in the Bone

Publications

Chronic Recurrent Multifocal Osteomyelitis in Children: A New, MRI-Based Method of Quantifying Inflammation in the Bone

Maecenas tempor, ex at maximus efficitur, felis sem ultrices ligula, ut hendrerit purus eros ac urna. Vestibulum ut vestibulum tortor. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Cras eu lectus quam. Nunc ligula arcu, auctor sit amet tellus eleifend, facilisis laoreet odio. Donec placerat urna eleifend blandit porttitor.

Nunc magna turpis, tristique at dictum vel, sollicitudin blandit felis. Morbi aliquam elit et pellentesque vulputate. Donec elementum, ante quis ornare porttitor, tortor dolor vestibulum velit, et viverra enim massa vitae ex.

Can the Pain DETECT Questionnaire Score and MRI Help Predict Treatment Outcome in Rheumatoid Arthritis: Protocol for the Frederiksberg Hospital’s Rheumatoid Arthritis, Pain Assessment and Medical Evaluation (FRAME-Cohort) Study

Publications

Can the Pain DETECT Questionnaire Score and MRI Help Predict Treatment Outcome in Rheumatoid Arthritis: Protocol for the Frederiksberg Hospital’s Rheumatoid Arthritis, Pain Assessment and Medical Evaluation (FRAME-Cohort) Study

Maecenas tempor, ex at maximus efficitur, felis sem ultrices ligula, ut hendrerit purus eros ac urna. Vestibulum ut vestibulum tortor. Orci varius natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Cras eu lectus quam. Nunc ligula arcu, auctor sit amet tellus eleifend, facilisis laoreet odio. Donec placerat urna eleifend blandit porttitor.

Nunc magna turpis, tristique at dictum vel, sollicitudin blandit felis. Morbi aliquam elit et pellentesque vulputate. Donec elementum, ante quis ornare porttitor, tortor dolor vestibulum velit, et viverra enim massa vitae ex.

MIMEDX and IAG Partner to Support Knee Osteoarthritis Ph 3 Clinical Trial Program

MIMEDX and IAG Partner to Support Knee Osteoarthritis Ph 3 Clinical Trial Program

Image Analysis Group to Partner with MIMEDX in Support of MIMEDX’s Knee Osteoarthritis Clinical Trial Program

Image Analysis Group to Provide Imaging Strategy and Advanced Imaging Analytics in Support of MIMEDX’s Knee Osteoarthritis Clinical Trial Program

MIMEDX is a transformational placental biologics company, developing and distributing placental tissue allografts and IAG, Image Analysis Group, a strategic bio-pharma imaging expert announce a partnership in the development of MIMEDX’s mdHACM.

The IAG team has significant experience in using medical imaging to support drug development.

‘We have significant evidence that mdHACM injected into the knees of people with OA provides lasting pain relief and improves function, and we believe it has potential as a DMOAD. MIMEDX has discovered how to preserve the remarkable healing properties of placental membranes when we produce mdHACM, and we have demonstrated that it contains many proteins that influence the biology of cartilage-forming cells and reduce inflammation. We believe these active proteins contribute to the striking, long-lasting benefits we have seen in patients receiving a single injection of mdHACM into their osteoarthritic knee. Following an extensive review and selection process, we are very excited to have world-class partners who are at the forefront of advancing meaningful medicines; working in collaboration accelerates our ability to gather quality data for our future Biologics License Application (BLA), and our potential to bring tremendous benefit for people living with OA.’ said Dr Robert B. Stein, M.D., Ph.D., MIMEDX President, Regenerative Medicine & Biologics Innovation.

About Image Analysis Group (IAG):

IAG, Image Analysis Group is a unique clinical development partner to life sciences companies. We broadly leverage our proprietary image analysis methodologies, power of our cloud platform DYNAMIKA, years of experience in AI and Machine Learning as well as bespoke co-development business models to ensure higher probability for promising therapeutics to reach the patients. Our independent Bio-Partnering division fuses risk-sharing business models and agile culture to accelerate novel drug development.

About MIMEDX: 

MIMEDX is a transformational placental biologics company, developing and distributing placental tissue allografts with patent-protected, proprietary processes for multiple sectors of healthcare. As a pioneer in placental tissue engineering, we have both a commercial business, focused on addressing the needs of patients with acute and chronic non-healing wounds, and a promising late-stage pipeline targeted at decreasing pain and improving function for patients with degenerative musculoskeletal conditions. We derive our products from human placental tissues and process these tissues using our proprietary methods, including the PURION® process. We employ Current Good Tissue Practices, Current Good Manufacturing Practices, and terminal sterilization to produce our allografts. MIMEDX has supplied over two million allografts, through both direct and consignment shipments.

For more information, please reach out to: imaging.experts@ia-grp.com

READ NEXT CASE STUDY >

Supporting Advance Imaging Research in Psoriatic Arthritis Treatment

Supporting Advance Imaging Research in Psoriatic Arthritis Treatment

Academic and Clinical Opinion Leaders and Image Analysis Group Collaborate to Advance Research in Psoriatic Arthritis Treatment.

London, UK — Image Analysis Group, a pioneer in medical imaging research and analysis, have joined forces in a strategic collaboration with renowned academic and clinical opinion leaders aimed at advancing research in the treatment of Psoriatic Arthritis, study MOSAIC, ClinicalTrials.gov Identifier: NCT03783026.

Amgen, known for its commitment to innovative therapies, recently presented the results of MOSAIC and its clinically relevant research findings on Otezla (Apremilast) in Psoriatic Arthritis during the European League Against Rheumatism (EULAR) 2023 annual meeting. The study, titled “Apremilast Reduces Inflammation as Measured by MRI of the Hand in Patients With Psoriatic Arthritis: Primary Results from the Phase 4 MOSAIC Study,” showcased the potential of Apremilast in reducing inflammation, as assessed through MRI scans of the hand.

This work is done in collaboration with MOSAIC study Primary Investigators Prof. Mease and Prof. Ostergaard, number of academic institutions and Image Analysis Group, an organization specializing in advanced medical imaging analysis and research.

This phase 4 trial and collected imaging and clinical data mark a significant step forward in drug developers’ mission to improve the lives of individuals affected by Psoriatic Arthritis. By harnessing the expertise and cutting-edge methodologies and advanced technology platform DYNAMIKA, Image Analysis Group and the collaborators aim to explore and quantify the impact of Apremilast on patients’ lives.

Image Analysis Group’s dedication to developing precise and comprehensive imaging solutions aligns seamlessly with Amgen’s commitment to scientific innovation, said Dr. Olga Kubassova, CEO of IAG.

We are excited to work in this trial with this dedicated group of people, so that our expertise in medical imaging analysis can support understanding and treatment of Psoriatic Arthritis, said Prof. Mikael Boesen, Sn Therapeutic Lead for Musculoskeletal Research at IAG and Head of musculoskeletal imaging and research, Bispebjerg and Frederiksberg Hospital, Radiology, Department of Overlæge, Professor, Bispebjerg and Frederiksberg Hospital, The Parker Institute , Denmark.

This work with Amgen and all collaborators signifies a shared vision of improving patient outcomes through innovation and imaging research.

For media inquiries, interview requests, or further information about this collaboration, please contact

imaging.experts@ia-grp.com

Image Analysis Group (IAG)

IAG, a pioneering imaging Clinical Research Organization (iCRO), seamlessly blends medical acumen, operational excellence, and cutting-edge AI to accelerate drug development. Since 2007, we’ve been the trusted partner for global biotech and pharma, expertly managing imaging across Phase I-III trials and real-world evidence studies in diverse therapeutic areas.

Our award-winning DYNAMIKA platform ensures unparalleled data integrity, while our innovative approach consistently unlocks and amplifies the value of novel therapies.

Partner with IAG to transform your clinical trials and maximize your therapeutic asset’s market potential.

READ NEXT CASE STUDY >