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MIMEDX and IAG Partner to Support Knee Osteoarthritis Ph 3 Clinical Trial Program

MIMEDX and IAG Partner to Support Knee Osteoarthritis Ph 3 Clinical Trial Program

Image Analysis Group to Partner with MIMEDX in Support of MIMEDX’s Knee Osteoarthritis Clinical Trial Program

Image Analysis Group to Provide Imaging Strategy and Advanced Imaging Analytics in Support of MIMEDX’s Knee Osteoarthritis Clinical Trial Program

MIMEDX is a transformational placental biologics company, developing and distributing placental tissue allografts and IAG, Image Analysis Group, a strategic bio-pharma imaging expert announce a partnership in the development of MIMEDX’s mdHACM.

The IAG team has significant experience in using medical imaging to support drug development.

‘We have significant evidence that mdHACM injected into the knees of people with OA provides lasting pain relief and improves function, and we believe it has potential as a DMOAD. MIMEDX has discovered how to preserve the remarkable healing properties of placental membranes when we produce mdHACM, and we have demonstrated that it contains many proteins that influence the biology of cartilage-forming cells and reduce inflammation. We believe these active proteins contribute to the striking, long-lasting benefits we have seen in patients receiving a single injection of mdHACM into their osteoarthritic knee. Following an extensive review and selection process, we are very excited to have world-class partners who are at the forefront of advancing meaningful medicines; working in collaboration accelerates our ability to gather quality data for our future Biologics License Application (BLA), and our potential to bring tremendous benefit for people living with OA.’ said Dr Robert B. Stein, M.D., Ph.D., MIMEDX President, Regenerative Medicine & Biologics Innovation.

About Image Analysis Group (IAG):

IAG, Image Analysis Group is a unique clinical development partner to life sciences companies. We broadly leverage our proprietary image analysis methodologies, power of our cloud platform DYNAMIKA, years of experience in AI and Machine Learning as well as bespoke co-development business models to ensure higher probability for promising therapeutics to reach the patients. Our independent Bio-Partnering division fuses risk-sharing business models and agile culture to accelerate novel drug development.

About MIMEDX: 

MIMEDX is a transformational placental biologics company, developing and distributing placental tissue allografts with patent-protected, proprietary processes for multiple sectors of healthcare. As a pioneer in placental tissue engineering, we have both a commercial business, focused on addressing the needs of patients with acute and chronic non-healing wounds, and a promising late-stage pipeline targeted at decreasing pain and improving function for patients with degenerative musculoskeletal conditions. We derive our products from human placental tissues and process these tissues using our proprietary methods, including the PURION® process. We employ Current Good Tissue Practices, Current Good Manufacturing Practices, and terminal sterilization to produce our allografts. MIMEDX has supplied over two million allografts, through both direct and consignment shipments.

For more information, please reach out to: imaging.experts@ia-grp.com

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IAG announced new partnership in development of novel, targeted T-cell enhancing immuno-oncology therapeutics

Pieris Pharmaceuticals, Inc. and Image Analysis Group Partner to use advanced imaging strategies to develop monoclonal antibody therapeutics against solid tumors.

BOSTON, MA, USA and LONDON, UK – April 16,  2020

IAG has partnered with the Boston-based Pieris Pharmaceuticals, Inc. to use quantitative image analysis methodologies, such as Radiomics to develop their novel asset, which is a monoclonal antibody therapeutic agent against solid tumors.

In this collaboration, IAG will provide expertise on the imaging methodologies, which include Computed tomography (CT) radiomics as a means of early detection of tumor’s response to therapy. This approach is poised to not only provide invigorating scientific endpoints but also offer the means to design and execute trials in a more efficient way.

Dr Olga Kubassova of IAG comments, “We are very excited to partner with Pieris on this project, in which we leverage Radiomics  in  the development of a very promising immunotherapeutic agent. There is tremendous potential in this methodology, not only as a standalone but even more so when combined with genomics and pathomics.”

Markus Ziettl, the CMO of Pieris shares his thoughts about this project, “Radiomics is a very exciting image analysis approach that provides non-invasive imaging biomarkers that work as surrogate markers for outcomes. When correlated with clinicopathologic outcomes, radiomic signatures can not detect the immunotherapy response earlier but also more accurately.”

ABOUT PARTNERS:

Pieris Pharmaceuticals, Inc. (NASDAQ:PIRS) Pieris is a clinical-stage biotechnology company that combines leading protein engineering capabilities and deep understanding into molecular drivers of disease to develop medicines that drive local biology to produce superior clinical outcomes for patients. Our pipeline is focused on inhalable Anticalin proteins to treat respiratory diseases and locally-activated bispecifics for immuno-oncology. Proprietary to Pieris, Anticalin proteins are a novel class of therapeutics validated in the clinic and by strong partnerships with leading pharmaceutical companies.

IAG, Image Analysis Group is a leadering imaging expert organization that provides cutting-edge advanced imaging methodology-based services in the realm of drug discovery and development. IAG has experts in Immuno-oncology, Neuroradiology, Molecular imaging and Musculoskeletal imaging. IAG has partnered with several major medical centers on one hand, such as University College London and McMaster University, and numerous biopharma/biotech companies in the realm of translational medicine and drug development on the other. IAG is a unique clinical development partner to life sciences companies and has a proprietary cloud-based platform DYNAMIKA for all image analysis needs. We have years of experience in AI and Machine Learning as well as bespoke co-development business models that ensure higher probability for promising therapeutics to reach the patients. Our independent Bio-Partnering division fuses risk-sharing business models and agile culture to accelerate novel drug development.

Supporting Advance Imaging Research in Psoriatic Arthritis Treatment

Supporting Advance Imaging Research in Psoriatic Arthritis Treatment

Academic and Clinical Opinion Leaders and Image Analysis Group Collaborate to Advance Research in Psoriatic Arthritis Treatment.

London, UK — Image Analysis Group, a pioneer in medical imaging research and analysis, have joined forces in a strategic collaboration with renowned academic and clinical opinion leaders aimed at advancing research in the treatment of Psoriatic Arthritis, study MOSAIC, ClinicalTrials.gov Identifier: NCT03783026.

Amgen, known for its commitment to innovative therapies, recently presented the results of MOSAIC and its clinically relevant research findings on Otezla (Apremilast) in Psoriatic Arthritis during the European League Against Rheumatism (EULAR) 2023 annual meeting. The study, titled “Apremilast Reduces Inflammation as Measured by MRI of the Hand in Patients With Psoriatic Arthritis: Primary Results from the Phase 4 MOSAIC Study,” showcased the potential of Apremilast in reducing inflammation, as assessed through MRI scans of the hand.

This work is done in collaboration with MOSAIC study Primary Investigators Prof. Mease and Prof. Ostergaard, number of academic institutions and Image Analysis Group, an organization specializing in advanced medical imaging analysis and research.

This phase 4 trial and collected imaging and clinical data mark a significant step forward in drug developers’ mission to improve the lives of individuals affected by Psoriatic Arthritis. By harnessing the expertise and cutting-edge methodologies and advanced technology platform DYNAMIKA, Image Analysis Group and the collaborators aim to explore and quantify the impact of Apremilast on patients’ lives.

Image Analysis Group’s dedication to developing precise and comprehensive imaging solutions aligns seamlessly with Amgen’s commitment to scientific innovation, said Dr. Olga Kubassova, CEO of IAG.

We are excited to work in this trial with this dedicated group of people, so that our expertise in medical imaging analysis can support understanding and treatment of Psoriatic Arthritis, said Prof. Mikael Boesen, Sn Therapeutic Lead for Musculoskeletal Research at IAG and Head of musculoskeletal imaging and research, Bispebjerg and Frederiksberg Hospital, Radiology, Department of Overlæge, Professor, Bispebjerg and Frederiksberg Hospital, The Parker Institute , Denmark.

This work with Amgen and all collaborators signifies a shared vision of improving patient outcomes through innovation and imaging research.

For media inquiries, interview requests, or further information about this collaboration, please contact

imaging.experts@ia-grp.com

Image Analysis Group (IAG)

IAG, a pioneering imaging Clinical Research Organization (iCRO), seamlessly blends medical acumen, operational excellence, and cutting-edge AI to accelerate drug development. Since 2007, we’ve been the trusted partner for global biotech and pharma, expertly managing imaging across Phase I-III trials and real-world evidence studies in diverse therapeutic areas.

Our award-winning DYNAMIKA platform ensures unparalleled data integrity, while our innovative approach consistently unlocks and amplifies the value of novel therapies.

Partner with IAG to transform your clinical trials and maximize your therapeutic asset’s market potential.

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Supportting Advance Imaging Research in Women’s Reproductive Health

Supportting Advance Imaging Research in Women’s Reproductive Health

Ferring Pharmaceuticals and Image Analysis Group Collaborate to Advance Research in the complex field of pregnancy.

London, UK — Image Analysis Group, a leader in medical imaging, have joined forces in a strategic collaboration with Ferring Pharmaceuticals to advance Women’s Reproductive Health through AI-driven medical image analysis.

Dr. Philippe Pinton, Senior Vice President, Head of Clinical and Translational Sciences, Global R&D at Ferring Pharmaceuticals, stated, “Our collaboration with IAG is a testament to our commitment to AI-driven research in the complex field of pregnancy.”

Dr. Olga Kubassova, CEO of IAG, added, “We are excited to support the Ferring team in leveraging AI to gain deeper insights into women’s reproductive health, ultimately aiming to enhance the chances of a healthy pregnancy for women globally.”

IAG’s mission is to assist pharmaceutical partners in efficiently developing transformative medicines. This is achieved through their expertise in medical imaging and AI, utilizing their proprietary platform, DYNAMIKA. This platform is designed to efficiently manage large volumes of imaging data in multi-centre trials and incorporates integrated AI modules. The partnership promises innovative approaches to improve women’s health worldwide.

For media inquiries, interview requests, or further information about this collaboration, please contact

imaging.experts@ia-grp.com

About Image Analysis Group: Image Analysis Group is a leading advanced medical imaging research and analysis services provider. With a focus on precision and scientific rigour, Image Analysis Group collaborates with pharmaceutical companies, research institutions, and healthcare providers to enhance the understanding of diseases and support the development of novel treatments.

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