Michael Brun Andersen
Michael Brun Andersen

Dr. Michael Brun Andersen MD, PhD

Therapeutic Area
Cardiology Musculoskeletal Oncology
Key Indicator Area
AI in Radiology CT Biomarkers Dual Energy CT Lung Cancer Imaging
Expertise Areas
Clinical Trialist Imaging Scientist Regulatory Advisor Translational Researcher

About Michael Brun Andersen

Current role and clinical setting

Dr. Michael Brun Andersen is Consultant Radiologist (Overlæge) at Copenhagen University Hospital Herlev and Gentofte, a position he has held since June 2019. He is Clinical Associate Professor in the Department of Clinical Medicine at the University of Copenhagen, a position he has held since December 2024. He is affiliated with the Radiology department at Herlev-Gentofte Hospital through the Faculty of Health Sciences, Department of Clinical Medicine, University of Copenhagen. He was elected Chairman of the Danish Lung Radiology Society during the COVID-19 pandemic. At IAG, Image Analysis Group, he serves as Scientific Advisor in Pulmonary Medicine and Imaging.

Therapeutic focus and research methodology

Dr. Andersen’s primary research focus is advanced diagnostic imaging of lung diseases, with particular depth in lung cancer and infectious lung diseases including pneumonia. His methodological contributions encompass the development of methodologies for quantitative computed tomography, CT texture analysis (CTTA) as a predictor of overall survival in non-small cell lung cancer (NSCLC), differentiation between malignant and benign lymph nodes in the mediastinum using CT texture analysis, and dynamic contrast-enhanced CT (DCE-CT) parameters as functional imaging biomarkers in NSCLC patients undergoing immunotherapy.

 

His more recent work has expanded to include photon-counting CT for improved pulmonary embolism imaging, image quality assessment of photon-counting CT for prostate cancer radiotherapy, AI-based algorithms to detect heart and lung disease from acute chest CT scans, prompt engineering for open-source large language models in radiology report annotation, handheld ultrasound devices for pneumonia diagnosis in emergency departments, ultra-low-dose CT for community-acquired pneumonia, and deep learning approaches to stroke MRI analysis. He collaborates with DTU Compute and international partners and has contributed to guidelines for diagnostic practices in pulmonary disease. He has also contributed to studies on occupational exposure to respirable crystalline silica and its relation to interstitial lung diseases.

Clinical trial experience

Dr. Andersen is named as a contributor on the BONY-M Phase 2 trial — a study of stereotactic ablative radiation therapy of bone metastases in an oligometastatic setting — with one-year follow-up published in the International Journal of Radiation Oncology, Biology, Physics (2026). He contributed to the prospective clinical proof-of-concept validation study of AI for detecting acute heart failure on chest CT (European Radiology Experimental 2026), which is structured as a prospective clinical study. He contributed to the AI-based algorithm development and validation protocol for detecting heart and lung disease from acute chest CT scans, published in JMIR Research Protocols (2025). He contributed to the multicenter diagnostic accuracy study of handheld ultrasound devices for pneumonia in emergency departments (Diagnostics 2024) and the diagnostic accuracy study of ultra-low-dose CT for community-acquired pneumonia (Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2024).

External recognition and standing

Dr. Andersen has 62 publications listed on ResearchGate with 819 citations and 35 publications indexed on the University of Copenhagen research profile. He was elected Chairman of the Danish Lung Radiology Society during the COVID-19 pandemic. His work has appeared in journals including European Radiology Experimental, Clinical Radiology, Cancer Imaging, Diagnostics, Acta Oncologica, International Journal of Radiation Oncology Biology Physics, and JMIR Research Protocols.

Background and training

Dr. Andersen completed his Cand. Med (MD) degree from the University of Copenhagen (2000 to 2007). He completed his PhD at Aarhus University, with his doctoral thesis entitled “Advanced Computed Tomography and Post-Processing Techniques in Patients with Lung Cancer.” He worked as a Radiologist (Læge radiolog) at Rigshospitalet from November 2012 to October 2014, and as Afdelingslæge (specialist registrar) at Roskilde Sygehus from November 2014 to May 2019. He has been Consultant Radiologist at Copenhagen University Hospital Herlev and Gentofte since June 2019, and Clinical Associate Professor at the University of Copenhagen since December 2024.

Recent Publications

Title Journal Year Link
Artificial intelligence for detecting acute heart failure on chest CT: prospective clinical proof-of-concept validation
European Radiology Experimental
2026
DCE-CT parameters as new functional imaging biomarkers at baseline and during immune checkpoint inhibitor therapy in patients with lung cancer — a feasibility study
Cancer Imaging
2024
Handheld ultrasound devices used by newly certified operators for pneumonia in the emergency department — a diagnostic accuracy study
Diagnostics
2024
Prompt engineering enables open-source LLMs to match proprietary models in diagnostic accuracy for annotation of radiology reports
Clinical Radiology
2026
AI-based algorithm to detect heart and lung disease from acute chest CT scans: protocol for an algorithm development and validation study
JMIR Research Protocols
2025

Appointments and advisory roles

Hospital / Clinical / Organization

Consultant Radiologist (Overlæge) Copenhagen University Hospital Herlev and Gentofte (since June 2019)
Clinical Associate Professor Department of Clinical Medicine, University of Copenhagen (since December 2024)
Scientific Advisor IAG, Image Analysis Group

Society leadership & boards

Chairman (during COVID-19 pandemic) Danish Lung Radiology Society

Education and training

Year Qualification / Role Institution
2024 – present
Clinical Associate Professor, Department of Clinical Medicine
University of Copenhagen
2022
PhD — “Advanced Computed Tomography and Post-Processing Techniques in Patients with Lung Cancer”
Aarhus University
2019 – present
Consultant Radiologist (Overlæge)
Copenhagen University Hospital Herlev and Gentofte
2014 – 2019
Afdelingslæge (Specialist Registrar in Radiology)
Roskilde Sygehus
2012 – 2014
Læge radiolog (Radiologist)
Rigshospitalet
2000 – 2007
Cand. Med (MD)
University of Copenhagen
Professional profiles & society links
Office Location Department of Radiology Copenhagen University Hospital Herlev and Gentofte Denmark
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